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Scientists produce painstaking wiring diagram of a mouse's brain

Scientists produce painstaking wiring diagram of a mouse's brain

Researchers Bethanny Danskin and Leila Elabbady examine high-resolution brain imaging and corresponding neuronal reconstructions from the MICrONS dataset at an Allen Institute laboratory in Seattle on Wednesday.

 Allen Institute

WASHINGTON 鈥� Neuroscientists have produced the largest wiring diagram and functional map of a mammalian brain to date, using tissue from a part of a mouse's cerebral cortex involved in vision, an achievement that could offer insight into how the human brain works.

They worked out the cerebral architecture in a tissue sample the size of a grain of sand bearing more than 200,000 cells, including roughly 84,000 nerve cells, called neurons, and about 524 million connections between these neurons at junctions called synapses. In all, they collected data that covers about 3.4 miles of neuronal wiring in a part of the brain that processes visual information from the eyes.



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